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Intermittent Fasting: A Key to Living Longer? Explained

Oct 6, 2025

6 min read

Written by Fluent Team

Medically reviewed by

Dt Vaishali M Marathe

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Intermittent Fasting: A Key to Living Longer? Explained

Intermittent fasting is not a trendy diet, but a proven lifestyle choice that is being adopted worldwide. It is a widely recognised weight control method that many individuals adopt, as it enables them to experience increased energy levels and several health benefits.

However, recent research has taken the effects of intermittent fasting beyond a weight loss tool to a process that can lengthen lifespan. It has been suggested that such a food habit can influence other activities, such as cell repair, hormonal balance, and metabolic well-being, which have a close correlation with the ageing process. Intermittent fasting and its connection to longevity are areas of research across a range of scientific disciplines, including nutrition, biology, and ageing studies.

Is the secret to a long, healthy life really intermittent fasting? Let’s investigate the science of fasting, its possible advantages, as well as the most important factors related to fasting longevity.

What is intermittent fasting?

Intermittent fasting is a pattern of eating in which one switches between intervals of eating and fasting. Unlike conventional diets, which emphasise the types of food to consume, intermittent fasting focuses on the timing of meals. Popular approaches include eating daily with limited time, alternating-day fasting, or fasting once or twice a week. It has several patterns: 12 -12 window, 8-16 window means 12 hrs fasting 12 hrs eating window, 8 hrs eating window 16hrs fasting.

The body also switches to using the stored energy during fasting periods when ready energy is unavailable. This process enables cells to switch to repair states, which might not be operative in normal eating patterns. In the long run, research suggests that such processes can result not only in improvements in general health but also in an extended lifespan.

Intermittent fasting is not as difficult to sustain as traditional diets, as some individuals do not have to strictly eliminate any food. Rather, it encourages a disciplined regimen that can lead to long-term health benefits and weight control.

Did You Know?

Unlike conventional diets, which emphasise the types of food to consume, intermittent fasting focuses on the timing of meals

The science behind fasting and longevity

The relationship between intermittent fasting, longevity, and better health lies in the realm of biological science. Studies show that fasting affects many of the pathways involved in ageing and the prevention of chronic diseases.

1. Cell repair and autophagy:
During fasting, the body triggers autophagy, a process that involves the degradation and recycling of damaged cells and proteins. This can prevent tissue damage and aid healthy ageing. It has been observed that increased autophagy can minimise the prevalence of age-related diseases and enhance cellular efficiency. Where diet should be inclusive of the right amount of proteins and other nutrients.

2. Reduced oxidative stress:
When the body experiences an imbalance between free radicals and antioxidants, this leads to oxidative stress. Persistent oxidative stress exacerbates aging and contributes to numerous health issues. Intermittent fasting is also found to reduce oxidative damage through better natural defence mechanisms of the body. Inclusion of more vegetables and fruits is mandatory.

3. Improved metabolic health:
Intermittent fasting has been shown to enhance insulin sensitivity, normalise blood sugar levels, and improve metabolic flexibility. This implies that the body can more easily alternate between burning glucose and fat as a source of energy, a vital aspect of long-term health.

4. Hormonal balance and ageing:
Fasting also affects several hormones that regulate growth, repair, and energy utilisation. Hormonal changes can be utilised to maintain youthful physiological functions and promote overall health.

Quick Explainer

Autophagy is a process that involves the degradation and recycling of damaged cells and proteins.

Can fasting help you live longer?

The central question many researchers explore is: Can fasting help you live longer? Although there is strong evidence that this may be the case in animal studies, human studies are in the nascent stages.

Animal studies have repeatedly demonstrated that intermittent fasting can prolong life by increasing stress resistance and decreasing age-related illnesses. Rodent and primate studies have demonstrated that physical performance, cognitive abilities, and overall survival rates are enhanced with adherence to fasting protocols.

Human studies are more complicated and promising. Intermittent fasting has been shown to be associated with improved biomarkers, including reduced inflammation rates, blood sugar levels, and body fat, in participants. These gains raise the possibility that not only lifespan may improve because of fasting, but also the quality of life.

Fun Fact

Animal studies have repeatedly demonstrated that intermittent fasting can prolong life by increasing stress resistance and decreasing age-related illnesses.

Long-term effects of intermittent fasting

Understanding the long-term effects of intermittent fasting is crucial for comprehending it as a lifestyle choice. Short-term effects, such as weight loss and increased energy, are well-documented, whereas the long-term effects of intermittent fasting, which can occur over years or decades, are under investigation.

Potential long-term benefits

  • Increased cellular repair and regeneration with regular autophagy promotion.
  • Better heart health measures, such as control of blood pressure.
  • Less chance of getting chronic illnesses associated with old age.
  • Improved brain performance and cognitive resilience due to the brain adjusting to the cycles of fasting.

Potential long-term risks

  • Malnutrition as a result of poor time management when eating.
  • Potential negative bone health impacts in the long term.
  • Hormonal disorders, particularly prevalent in persons with underlying health issues.
  • Uncontrolled diabetes or diabetic patient should avoid this for ketoacidosis

These dangers underscore the importance of planning attentively and being guided by a professional. A one-size-fits-all approach to fasting may not apply, and individuals may respond differently depending on their genetics, age, and lifestyle.

Quick Tip

Drink plenty of water throughout the fasting period to prevent dehydration.

How to practice intermittent fasting safely?

To maximise the benefits of fasting for longevity, safety must be a priority. Below are steps to ensure a safe and sustainable fasting routine:

  • Start small: You can start with shorter periods of fasting, like 12-hour fasts, and then increase to longer fasting.

  • Stay hydrated: Drink plenty of water throughout the fasting period to prevent dehydration. Drink low calorie liquids like buttermilk, thin dal water, clear veg soup to compensate for the hydration level and give satiety. It boost the metabolism.

  • Eat healthy foods: When eating, consider a balanced diet that involves whole foods that are rich in vital nutrients.

  • Keep track of your health: Be aware of any symptoms such as dizziness or excessive tiredness, and make necessary changes.

  • Consult a professional: Before starting a fasting program, consult a medical practitioner, especially if you have underlying health issues.

With these recommendations in place, intermittent fasting can be an effective, long-term, healthy, and sustainable strategy for promoting long-term health and well-being.

Final thoughts: Is intermittent fasting the key to longevity?

The connection between intermittent fasting and longevity is convincing and subject to current scientific research. Although there is evidence, especially in animals, that strongly suggests potential benefits, larger-scale human research is needed to establish definitive findings.

Intermittent fasting promotes various biological functions that can help prevent ageing and improve overall health. Nonetheless, it is not an independent solution. The lifespan of an individual depends on genetic factors, environmental factors, stress, and the individual's overall lifestyle habits. Always consult a specialist before starting to do it in right way and avoid complication

Intermittent fasting can be very important as part of a healthy lifestyle that includes a balanced diet, regular exercise, and other healthy behaviours.

Frequently Asked Questions

1. What is the safest way to begin intermittent fasting?

Starting with short periods of fasting, then gradually increasing, keeping hydrated, and eating foods rich in nutrients are the safest ways to go. It is advisable to consult a medical practitioner prior to commencing. It should be done under professional guidance.

2. Is the long-term effect of intermittent fasting harmful?

Otherwise, intermittent fasting would cause nutritional deficiencies, hormonal imbalances or other health problems. It is essential to prevent complications by planning and regularly monitoring balanced meals.

3. Is intermittent fasting effective?

The reactions to intermittent fasting vary from person to person. The benefits and risks of fasting can be influenced by factors such as age, genetics, and pre-existing health conditions.

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